Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2777881 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL387981 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL6142328 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL6465548 | 0.77 | MEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7564378 | 0.71 | MAOA (0.37) | — | |
| Hydrochloric Acid SCHEMBL2777393 | 0.69 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL846609 | 0.69 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6453947 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL6459144 | 0.68 | CEL (0.30) | — | |
| Hydrochloric Acid SCHEMBL5184073 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4658326-B2 | — | — | 2011-03-23 | — | — | JP | claimed |
| EP-1049704-B1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-27 | — | — | EP | claimed |
| JP-2002530413-A | — | — | 2002-09-17 | — | — | JP | claimed |
| US-6433203-B1 | COORDINATION POLYMERIZATION CATALYST; ALPHA-OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-08-13 | — | — | US | claimed |
| EP-1049704-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | Montell Technology Company bv (NL) | 2000-11-08 | — | — | EP | claimed |
| WO-2000031088-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-06-02 | — | — | WO | claimed |
| EP-2177543-B1 | Hybrid catalyst composition for polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-8435911-B2 | Hybrid catalyst composition for polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-05-07 | — | — | US | disclosed |
| EP-1620448-B1 | PROCESS FOR THE PRODUCTION OF HALIDE METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2010-06-16 | — | — | EP | disclosed |
| US-20100099825-A1 | Hybrid catalyst composition for polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2010-04-22 | — | — | US | disclosed |
| EP-2177543-A1 | Hybrid catalyst composition for polymerization of olefins | Basell Polyolefine GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-7468451-B2 | Process for the production of halide metallocene compounds | BASELL POLYOLEFINE GMBH (DE) | 2008-12-23 | — | — | US | disclosed |
| EP-1381618-B1 | PROCESS FOR THE PRODUCTION OF MONOHALIDE OR DIHALIDE METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2008-05-07 | — | — | EP | disclosed |
| US-20060025621-A1 | Process for the production of monohalide or dihalide metallocene compounds | BASELL POLYOLEFINE GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
| US-6987196-B2 | Process for the production of monohalide or dihalide metallocene compounds | BASELL POLYOLEFINE GMBH (DE) | 2006-01-17 | — | — | US | disclosed |
| EP-1049704-B1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-20040147770-A1 | Process for the production of monohalide or dihalide metallocene compounds | EQUISTAR CHEMICALS, LP | 2004-07-29 | — | — | US | disclosed |
| US-6433203-B1 | COORDINATION POLYMERIZATION CATALYST; ALPHA-OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-08-13 | — | — | US | disclosed |
| EP-1049704-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | Montell Technology Company bv (NL) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000031088-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-06-02 | — | — | WO | disclosed |