Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786716 | 0.98 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL388143 | 0.98 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL388142 | 0.98 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL387760 | 0.96 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15085946 | 0.88 | TP53 (0.56) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5498513 | 0.87 | MEN1 (0.46) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL12561790 | 0.87 | RECQL (0.53) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739481 | 0.84 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10739476 | 0.84 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27415288 | 0.84 | RAB9A (0.50) | AKR1C3ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746410-A4 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INST OF TECHN (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0746410-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022405-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-08-24 | — | — | WO | disclosed |