Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892994 | 0.94 | HRH3 (0.54) | HRH3SIGMAR1GRIN2B | |
| Methyl Alcohol SCHEMBL27755634 | 0.90 | HRH3 (0.50) | HRH3SIGMAR1 | |
| SCHEMBL3891265 | 0.87 | TEAD3 (0.60) | HRH3SIGMAR1 | |
| SCHEMBL7246438 | 0.87 | TEAD3 (0.60) | HRH3SIGMAR1 | |
| SCHEMBL6725705 | 0.86 | HRH3 (0.49) | HRH3SIGMAR1 | |
| SCHEMBL3959376 | 0.84 | SIGMAR1 (0.72) | SIGMAR1GRIN2B | |
| SCHEMBL7845393 | 0.84 | SLC6A3 (0.56) | HRH3SIGMAR1 | |
| SCHEMBL6705256 | 0.83 | SIGMAR1 (0.67) | SIGMAR1GRIN2B | |
| SCHEMBL6944485 | 0.82 | TEAD3 (0.55) | HRH3 | |
| SCHEMBL8108121 | 0.82 | TEAD3 (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029958-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | US | disclosed |
| EP-2013197-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007102771-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029958-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ADRB2, ADRB1, ADRA2A | HRH3 21/4885SIGMAR1 1619/4885GRIN2B 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.