Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15927269 | 0.82 | ACHE (0.32) | ACHEEPHX1ALOX15KMT2A | |
| SCHEMBL3883873 | 0.81 | ACHE (0.34) | ACHEEPHX1LMNAALOX15ALDH1A1 | |
| SCHEMBL3882369 | 0.80 | CHRNB2 (0.31) | LMNAALDH1A1 | |
| SCHEMBL18848363 | 0.79 | ALDH1A1 (0.36) | ACHEEPHX1LMNAALOX15ALDH1A1 | |
| SCHEMBL18848221 | 0.79 | ALDH1A1 (0.36) | ACHEEPHX1LMNAALOX15ALDH1A1 | |
| SCHEMBL18848280 | 0.79 | ALDH1A1 (0.36) | ACHEEPHX1LMNAALOX15ALDH1A1 | |
| SCHEMBL3894832 | 0.79 | MEN1 (0.34) | KMT2A | |
| SCHEMBL3893762 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL3884111 | 0.78 | ACHE (0.45) | ACHEEPHX1EPHX2 | |
| SCHEMBL1883974 | 0.78 | ALDH1A1 (0.35) | ACHEEPHX1LMNAALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566738-B2 | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use | XENOPORT, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20060111439-A1 | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use | XENOPORT, INC. | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111439-A1 | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use | ASS1, APEH, ACMSD | ACHE 450/4885EPHX1 987/4885LMNA 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.