Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892574 | 0.75 | MEP1B (0.54) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL23014305 | 0.75 | MEP1B (0.60) | MEP1BMMP1TSHRNPSR1CA1 | |
| SCHEMBL28677877 | 0.74 | KDM4E (0.71) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL6850445 | 0.73 | MEP1B (0.62) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL23014492 | 0.72 | KMT2A (0.59) | MEP1BMMP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6505407 | 0.72 | ALDH1A1 (0.68) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL5899482 | 0.72 | L3MBTL1 (0.60) | MEP1BMMP1ALDH1A1MMP2MMP9 | |
| SCHEMBL11708062 | 0.71 | MEP1B (0.68) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL27548886 | 0.70 | CA1 (0.58) | MEP1BMMP1ALDH1A1TSHRNPSR1 | |
| SCHEMBL8285177 | 0.70 | MEP1B (0.62) | MEP1BMMP1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013184-A1 | SULFONAMIDE COMPOUNDS USEFUL AS EDG RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007129019-A1 | SULFONAMIDE COMPOUNDS USEFUL AS EDG RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | disclosed |