Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880217 | 0.86 | CNR2 (0.57) | RHEBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1993195 | 0.84 | SERPINE1 (0.55) | SLC22A12FABP4SERPINE1LMNAALDH1A1 | |
| SCHEMBL8599922 | 0.83 | SLC22A12 (0.74) | SLC22A12FABP4PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8598410 | 0.82 | SLC22A12 (0.72) | SLC22A12FABP4PDE4APDE4BPDE4C | |
| SCHEMBL21439305 | 0.81 | RHEB (0.67) | RHEBFABP4SERPINE1LMNAALDH1A1 | |
| SCHEMBL28018754 | 0.77 | KMT2A (0.58) | LMNAALDH1A1ADORA1MEN1KMT2A | |
| SCHEMBL2510390 | 0.76 | LMNA (0.54) | LMNAALDH1A1ADORA1MEN1KMT2A | |
| SCHEMBL1991908 | 0.75 | ADRA1D (0.55) | SLC22A12SERPINE1PDE4APDE4BPDE4C | |
| SCHEMBL8598408 | 0.74 | PDE4A (0.64) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2418393 | 0.74 | ALDH1A1 (0.46) | SLC22A12ALDH1A1MAPK10MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | RHEB 2105/4885SLC22A12 2522/4885FABP4 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.