Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764749 | 0.82 | VCAM1 (0.47) | VCAM1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9573845 | 0.82 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27633703 | 0.79 | KDM4E (0.44) | ALDH1A1GCGRMAPK14MAPTHTT | |
| SCHEMBL6561277 | 0.79 | KIF11 (0.49) | ALDH1A1MAPTSMN1; SMN2KIF11 | |
| SCHEMBL9390186 | 0.78 | AR (0.54) | KIF11 | |
| SCHEMBL10590631 | 0.78 | AR (0.54) | RAD51ALDH1A1HPGDPOLB | |
| SCHEMBL3890191 | 0.78 | PTGES (0.38) | RAD51KIF11 | |
| SCHEMBL3893100 | 0.78 | KDM4E (0.46) | ALDH1A1LMNAHPGDHTTMEN1 | |
| SCHEMBL9193868 | 0.77 | MAOA (0.45) | ALDH1A1MAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL9228453 | 0.77 | KIF11 (0.41) | VCAM1SCN2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531702-B1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-subst. -5-(trifluoromethyl)pyrrole compounds from N-(subst. benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | BASF AG (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-0531702-A1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substitued-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5145986-A | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoro-acetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1992-09-08 | — | — | US | disclosed |