Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996382 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996381 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996383 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3887795 | 0.78 | PTGES (0.43) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3887780 | 0.78 | PTGES (0.43) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3892755 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3892003 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3893611 | 0.68 | NOS3 (0.32) | — | |
| SCHEMBL3893609 | 0.68 | NOS3 (0.32) | — | |
| SCHEMBL28704993 | 0.66 | CA9 (0.50) | ALDH1A1MEN1KMT2ACA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |