Sugi Predict

Sugi Predict / Compounds / SCHEMBL3894503

SCHEMBL3894503

SCHEMBL3894503

Cc1ccccc1-c1nc(N)nc(N)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 2/20 0.71
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ ALDH1A1 P00352 2/20 0.55
▸ ADORA2A P29274 4/20 0.53
▸ ADORA3 P0DMS8 2/20 0.50
▸ ADORA2B P29275 2/20 0.50
▸ ADORA1 P30542 2/20 0.50
▸ HEXA P06865 1/20 0.50
▸ HEXB P07686 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ CYP1A2 P05177 4/20 0.49
▸ CYP2C19 P33261 4/20 0.49
▸ DHFR P00374 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ HPGD P15428 1/20 0.49
▸ ALOX15 P16050 3/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ CYP2D6 P10635 2/20 0.46
▸ CLK4 Q9HAZ1 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468191 0.84 SMN1; SMN2 (0.71) HSP90AA1SMN1; SMN2ALDH1A1ADORA2AADORA3
SCHEMBL17046876 0.84 SMN1; SMN2 (0.71) HSP90AA1SMN1; SMN2ALDH1A1ADORA2AADORA3
SCHEMBL11810775 0.84 HSP90AA1 (0.55) HSP90AA1SMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL125549 0.83 HSP90AA1 (0.53) HSP90AA1SMN1; SMN2ALDH1A1ADORA2AADORA3
SCHEMBL28233418 0.81 HSP90AA1 (0.54) HSP90AA1SMN1; SMN2ALDH1A1ADORA2AADORA1
SCHEMBL18216913 0.77 L3MBTL1 (0.54) HSP90AA1SMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL9566504 0.77 SMN1; SMN2 (0.63) HSP90AA1SMN1; SMN2ALDH1A1ADORA2AADORA3
SCHEMBL805591 0.76 HSP90AA1 (0.49) HSP90AA1SMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL9566561 0.75 RAB9A (0.52) HSP90AA1SMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL125550 0.75 RAB9A (0.52) HSP90AA1SMN1; SMN2ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5122590-A Addition-condensation copolymer comprising an N,N*-bismaleimide, hindered aromatic diprimary diamine, a diamino-s-triazine, a halogenated epoxy resin and a diallyl oxylated benzene; heat resistance; prepregs RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US claimed
US-5100767-A Epoxy resins TAMURA KAKEN CO., LTD. (JP) 1992-03-31 — — US claimed
CN-110337458-B Curable composition, electronic component, and method for producing electronic component 积水化学工业株式会社 2022-12-27 — — CN disclosed
CN-113461660-B 2,4, 6-trisubstituted-1, 3, 5-s-triazine compound, preparation and application thereof 浙江大学 2022-08-02 — — CN disclosed
CN-113461660-A 2,4, 6-trisubstituted-1, 3, 5-s-triazine compound, preparation and application thereof 浙江大学 2021-10-01 — — CN disclosed
EP-3837294-A1 ONE COMPONENT THERMOSETTING EPOXY RESIN COMPOSITIONS Sika Technology AG (CH) 2021-06-23 — — EP disclosed
CN-107531815-B Curable composition and method for producing electronic component 积水化学工业株式会社 2021-05-11 — — CN disclosed
WO-2020035288-A1 ONE COMPONENT THERMOSETTING EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2020-02-20 — — WO disclosed
EP-3611202-A1 SINGLE-COMPONENT HEAT CURING EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2020-02-19 — — EP disclosed
CN-110337458-A The manufacturing method of solidification compound, electronic component and electronic component 积水化学工业株式会社 2019-10-15 — — CN disclosed
US-20170348295-A1 SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA SIRGA ADVANCED BIOPHARMA INC (US) 2017-12-07 — — US disclosed
EP-0395981-B1 EXPANDABLE STYRENE POLYMERS BASF Aktiengesellschaft (DE) 1993-01-13 — — EP disclosed
US-5122590-A Addition-condensation copolymer comprising an N,N*-bismaleimide, hindered aromatic diprimary diamine, a diamino-s-triazine, a halogenated epoxy resin and a diallyl oxylated benzene; heat resistance; prepregs RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US disclosed
US-5100767-A Epoxy resins TAMURA KAKEN CO., LTD. (JP) 1992-03-31 — — US disclosed
US-4973610-A CONTAINING BLOWING AGENT, BROMINE COMPOUND, AMMONIUM COMPOUND, AND AMINE BASF AKTIENGESELLSCHAFT (DE) 1990-11-27 — — US disclosed
EP-0395981-A1 Expandable styrene polymers BASF Aktiengesellschaft (DE) 1990-11-07 — — EP disclosed
US-4501689-A CONTAINING PYRIDINE OR IMIDAZOLE MODIFIED 5-TRIAZINE TAMURA KAKEN CO., LTD. (JP) 1985-02-26 — — US disclosed
US-4320189-A A THERMOPLASTIC BINDER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-03-16 — — US disclosed
EP-0003799-B1 FINELY DIVIDED EXPANDABLE STYRENE POLYMERS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-04 — — EP disclosed
US-4192922-A Finely divided expandable styrene polymers HOECHST AKTIENGESELLSCHAFT (DE) 1980-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170348295-A1 SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA NSUN3, TARBP1, TRDMT1 HSP90AA1 1636/4885SMN1; SMN2 2805/4885ALDH1A1 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.