SCHEMBL62706

SCHEMBL62706

O=c1[nH]c2ccc(Cl)cc2c(=O)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
CYP1A2 P05177 2/20 0.58
ADRA2A P08913 1/20 0.58
TSHR P16473 1/20 0.58
NOS3 P29474 1/20 0.58
NOS1 P29475 1/20 0.58
NOS2 P35228 1/20 0.58
THPO P40225 1/20 0.58
BLM P54132 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
F2 P00734 1/20 0.56
CFD P00746 1/20 0.56
GAA P10253 2/20 0.50
HPGD P15428 1/20 0.50
MAOA P21397 6/20 0.49
MAOB P27338 6/20 0.49
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
ACHE P22303 2/20 0.47
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30908765 1.00 LMNA (0.58) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL30557808 0.85 LMNA (0.62) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL625761 0.85 LMNA (0.62) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL1202291 0.78 NOS1 (0.62) LMNANOS3NOS1NOS2F2
SCHEMBL3132671 0.78 MAOA (0.57) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL694149 0.78 MAOA (0.61) LMNAF2CFDGAAHPGD
SCHEMBL31460362 0.78 MAOA (0.57) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL14448380 0.78 F2 (0.56) LMNACYP1A2ADRA2ATSHRNOS3
SCHEMBL1147630 0.78 F2 (0.56) F2CFDMAOAMAOBCA12
SCHEMBL1668291 0.78 F2 (0.56) F2CFDGAAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 883 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 CN claimed
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 CN claimed
CN-117603144-A Synthesis method of polysubstituted quinazolinone 常熟泓德生物科技有限公司 2024-02-27 CN claimed
CN-110372611-B Method for selectively synthesizing polysubstituted dihydro quinazolinone or quinazolinone 常熟理工学院 2021-05-04 CN claimed
CN-110372611-A A kind of method of the polysubstituted dihydroquinazoline ketone of selectivity synthesis or quinazolinone 常熟理工学院 2019-10-25 CN claimed
US-9580394-B2 Benzodiazepine derivative and method of producing the same Atomic Energy Council—Institute of Nuclear Energy Research (TW) 2017-02-28 US claimed
US-20150252009-A1 BENZODIAZEPINE DERIVATIVE AND METHOD OF PRODUCING THE SAME ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2015-09-10 US claimed
US-20120009226-A1 HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF ACTAVIS GROUP PTC EHF (IS) 2012-01-12 US claimed
EP-2376456-A2 HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Actavis Group Ptc Ehf (IS) 2011-10-19 EP claimed
US-7772377-B2 Colorant compositions XEROX CORPORATION (US) 2010-08-10 US claimed
US-20040215002-A1 Colorant compositions XEROX CORPORATION 2004-10-28 US claimed
US-6790267-B1 METHINE COLORANT COMPOUNDS FOR PHASE CHANGE INKS XEROX CORPORATION 2004-09-14 US claimed
US-6764541-B1 Colorant compositions XEROX CORPORATION 2004-07-20 US claimed
US-6583248-B1 Methacrylate groups; dental cement AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2003-06-24 US claimed
US-6180739-B1 CYCLODEXTRINS WITH ACRYLATE AND ANHYDRIDES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2001-01-30 US claimed
US-5929131-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1999-07-27 US claimed
US-5792821-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1998-08-11 US claimed
US-4728673-A BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT BAYER AKTIENGESELLSCHAFT (DE) 1988-03-01 US claimed
US-4306074-A Preparation of a mixture of an alkyl 3-chloroanthranilate and an alkyl 6-chloroanthranilate BASF AKTIENGESELLSCHAFT (DE) 1981-12-15 US claimed
EP-0020969-A1 Process for the preparation of a mixture of 3-chloro-anthranilic acid alkyl ester and 6-chloro-anthranilic acid alkyl ester BASF Aktiengesellschaft (DE) 1981-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252009-A1 BENZODIAZEPINE DERIVATIVE AND METHOD OF PRODUCING THE SAME GABRA5, GABRA2, GABRA4 LMNA 772/4885CYP1A2 316/4885ADRA2A 692/4885
US-20120009226-A1 HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TLR7, MYD88, PDE7A LMNA 1496/4885CYP1A2 211/4885ADRA2A 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.