SCHEMBL2382755

SCHEMBL2382755

O=c1[nH]c2cc(Br)ccc2c(=O)o1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.56
▸ CFD P00746 1/20 0.56
▸ MAOA P21397 3/20 0.54
▸ MAOB P27338 3/20 0.54
▸ METAP2 P50579 1/20 0.47
▸ CDK5 Q00535 3/20 0.41
▸ CDK9 P50750 2/20 0.41
▸ CAMK2A Q9UQM7 2/20 0.41
▸ CCNB2 O95067 2/20 0.41
▸ CDK1 P06493 2/20 0.41
▸ CCNB1 P14635 2/20 0.41
▸ CDK5R1 Q15078 2/20 0.41
▸ CCNB3 Q8WWL7 2/20 0.41
▸ CCNT1 O60563 1/20 0.41
▸ CCNE2 O96020 1/20 0.41
▸ CDK4 P11802 1/20 0.41
▸ EIF2AK2 P19525 1/20 0.41
▸ CCNA2 P20248 1/20 0.41
▸ CCND1 P24385 1/20 0.41
▸ CCNE1 P24864 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30549739 1.00 F2 (0.56) F2CFDMAOAMAOBMETAP2
SCHEMBL29440610 0.85 MAOA (0.61) F2CFDMAOAMAOBCDK5
SCHEMBL389647 0.85 MAOA (0.61) F2CFDMAOAMAOBCDK5
SCHEMBL31607092 0.78 F2 (0.56) F2CFDMAOAMAOBCDK4
SCHEMBL3435898 0.78 NOS1 (0.62) F2CFDMAOAMAOBCAMK2A
SCHEMBL1202554 0.78 F2 (0.56) F2CFDMAOAMAOBCAMK2A
SCHEMBL12324556 0.78 F2 (0.56) F2CFDMAOAMAOBCDK5
SCHEMBL31607095 0.78 F2 (0.56) F2CFDMAOAMAOBCDK4
SCHEMBL30639060 0.78 F2 (0.56) F2CFDMAOAMAOBCAMK2A
SCHEMBL625761 0.78 LMNA (0.62) F2CFDLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120079371-A Oxygen vacancy-containing tungsten trioxide catalyst and preparation method and application thereof 南京理工大学 2025-06-03 — — CN claimed
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 — — CN claimed
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 — — CN claimed
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 — — CN claimed
EP-4730479-A2 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2026-04-22 — — EP disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 — — US disclosed
US-20250246685-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME KYOTO UNIVERSITY (JP) 2025-07-31 — — US disclosed
WO-2025120994-A1 SECONDARY BATTERY NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY PROVIDED WITH SAME ステラケミファ株式会社 2025-06-12 — — WO disclosed
CN-120079371-A Oxygen vacancy-containing tungsten trioxide catalyst and preparation method and application thereof 南京理工大学 2025-06-03 — — CN disclosed
EP-4551208-A1 PHARMACEUTICAL COMPOSITION, METHODS OF USE THEREOF FOR TREATING COCAINE ADDICTION, AND NOVEL USE OF HAUSP K444R POINT MUTANT MOUSE Pharwar Biotechnology, Inc. Pte. Ltd. (SG) 2025-05-14 — — EP disclosed
WO-2025095088-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR SECONDARY BATTERY, AND SECONDARY BATTERY PROVIDED WITH SAID SOLUTION ステラケミファ株式会社 2025-05-08 — — WO disclosed
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 — — CN disclosed
US-5733910-A Pyridazinedione compounds useful in the treating neurological disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-03-31 — — US disclosed
US-5604227-A EXCITATORY AMINO ACID ANTAGONIST; MONO, DI OR TRI-ACETYLATION OR ALKYLATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-02-18 — — US disclosed
US-5599814-A SUBSTITUTED PYRIDAZINO(4,5-B)QUINOLINES AS ANTAGONISTS OF EXCITATORY AMINO ACIDS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1997-02-04 — — US disclosed
EP-0516297-B1 Pyridazinediones and their use in the treatment of neurological disorders ZENECA LTD (GB) 1996-10-30 — — EP disclosed
EP-0516297-A1 Pyridazinediones and their use in the treatment of neurological disorders ZENECA LIMITED (GB) 1992-12-02 — — EP disclosed
EP-0135367-B1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1988-03-16 — — EP disclosed
US-4659718-A VASODILATION THE BOOTS COMPANY PLC (GB) 1987-04-21 — — US disclosed
EP-0135367-A1 Therapeutic agents The Boots Company PLC (GB) 1985-03-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA F2 1608/4885CFD 3168/4885MAOA 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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