Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900535 | 0.76 | NPC1 (0.43) | CDK1ALDH1A1EGLN1 | |
| SCHEMBL3900423 | 0.67 | F10 (0.43) | CDK1PDK1PDK2PDK3PDK4 | |
| SCHEMBL28223333 | 0.67 | KDR (0.41) | ALDH1A1KCNH2KDRPIK3CAPIK3CB | |
| SCHEMBL3905446 | 0.67 | KDM4E (0.40) | CYP11B1CYP11B2TTRPARP2PTGDR2 | |
| SCHEMBL3900652 | 0.66 | RAB9A (0.46) | CDK1F10EGLN1 | |
| SCHEMBL9850808 | 0.66 | MAPT (0.47) | ALDH1A1MAPTSLC6A3KCNH2KDR | |
| Hydrochloric Acid SCHEMBL3896102 | 0.65 | KDM4E (0.43) | CYP11B1CYP11B2ALDH1A1PARP2PTGDR2 | |
| SCHEMBL24022839 | 0.65 | CASP1 (0.44) | KCNH2KDRPIK3CAPIK3CBMTOR | |
| SCHEMBL3896082 | 0.65 | MMP3 (0.44) | CYP11B1CYP11B2TTREGLN1PTGDR2 | |
| SCHEMBL3571548 | 0.64 | TRPV4 (0.40) | MAPTSLC6A4KCNH2TTRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |