Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394413 | 0.89 | FAAH (0.72) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL391199 | 0.88 | FAAH (0.76) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL393982 | 0.85 | FAAH (0.65) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL395281 | 0.79 | FAAH (0.83) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL393500 | 0.78 | MAPT (0.81) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL393675 | 0.74 | FAAH (1.00) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL3655654 | 0.72 | MPO (0.76) | KMT2AMPOSLC6A4NOTUMMTNR1A | |
| SCHEMBL29902243 | 0.72 | MPO (0.76) | KMT2AMPOSLC6A4NOTUMMTNR1A | |
| SCHEMBL24863352 | 0.72 | FAAH (0.70) | FAAHMAPTMEN1KMT2APOLB | |
| SCHEMBL3220638 | 0.71 | MPO (0.74) | KMT2AMPOSLC6A4NOTUMMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101649-B2 | N-acylhydrazone derivatives useful as modulators of nicotinic acetylcholine receptors | NEUROSEARCH A/S (DK) | 2012-01-24 | — | — | US | disclosed |