Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200445 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL6155824 | 0.87 | TUBB1 (0.62) | ALDH1A1MAOBCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL3209556 | 0.87 | ALDH1A1 (0.69) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL3334328 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL5143351 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL702232 | 0.85 | ALDH1A1 (0.71) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL22090594 | 0.84 | HDAC8 (0.53) | ALDH1A1L3MBTL1CYP1A2TUBB1TDP1 | |
| SCHEMBL20535326 | 0.83 | PRKDC (0.47) | ALDH1A1MAOBL3MBTL1CYP1A2TUBB1 | |
| SCHEMBL1566049 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL14539352 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAOBL3MBTL1CYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707903-A | Isopentenyl flavonoid compound and preparation method and application thereof | 中山大学 | 2025-03-28 | — | — | CN | claimed |
| EP-4725942-A1 | COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE | Sibylla Biotech S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| CN-119707903-A | Isopentenyl flavonoid compound and preparation method and application thereof | 中山大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119504685-A | Benzopyran flavonoid compound, preparation method and application thereof, and pharmaceutical preparation | 南开大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-111184866-B | Combination treatment of bacterial infections | 香港中文大学 | 2023-12-19 | — | — | CN | disclosed |
| US-11690810-B2 | Combination treatment of bacterial infection | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2023-07-04 | — | — | US | disclosed |
| CN-111184866-A | Combination therapy for bacterial infections | 香港中文大学 | 2020-05-22 | — | — | CN | disclosed |
| US-20200155641-A1 | COMBINATION TREATMENT OF BACTERIAL INFECTION | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2020-05-21 | — | — | US | disclosed |
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-05-11 | — | — | US | disclosed |
| EP-1535915-A1 | FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155641-A1 | COMBINATION TREATMENT OF BACTERIAL INFECTION | PGC, NRDC, PYCARD | ALDH1A1 3345/4885MAOB 1068/4885L3MBTL1 2147/4885 |
| US-11690810-B2 | Combination treatment of bacterial infection | PGC, NRDC, PYCARD | ALDH1A1 3345/4885MAOB 1068/4885L3MBTL1 2147/4885 |
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TXN2, CYP11B2, CYP11B1 | ALDH1A1 1096/4885MAOB 2227/4885L3MBTL1 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.