Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477402 | 0.77 | APP (0.53) | L3MBTL1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL5016819 | 0.77 | L3MBTL1 (0.50) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL10903897 | 0.76 | L3MBTL1 (0.55) | L3MBTL1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL15366219 | 0.75 | MAOA (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1143540 | 0.74 | MAOB (0.53) | L3MBTL1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL329575 | 0.74 | ALOX5 (0.62) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9525385 | 0.73 | ALOX5 (0.53) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL8901906 | 0.73 | MAOB (0.56) | L3MBTL1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL3629799 | 0.73 | MAOB (0.56) | L3MBTL1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL10030221 | 0.73 | CYP1A2 (0.58) | ALOX5MEN1KMT2AMAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739390-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | Sitala Bio Ltd (GB) | 2026-05-13 | — | — | EP | disclosed |
| EP-4739676-A1 | 2-(1H-INDOL-4-YL)METHYL)-ISOINDOLINE DERIVATIVES AS FACTOR B INHIBITORS | Sitala Bio Ltd (GB) | 2026-05-13 | — | — | EP | disclosed |
| CN-120118068-A | Chemical process for preparing phenylpiperidinyl indole derivatives | 诺华股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-112513025-B | Chemical process for preparing phenylpiperidinyl indole derivatives | 诺华股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025008451-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | SITALA BIO LTD (GB) | 2025-01-09 | — | — | WO | disclosed |
| WO-2025008453-A1 | 2-(1H-INDOL-4-YL)METHYL)-ISOINDOLINE DERIVATIVES AS FACTOR B INHIBITORS | SITALA BIO LTD (GB) | 2025-01-09 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-11578053-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | NOVARTIS AG (CH) | 2023-02-14 | — | — | US | disclosed |
| US-20220169630-A1 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2022-06-02 | — | — | US | disclosed |
| US-11208398-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | NOVARTIS AG (CH) | 2021-12-28 | — | — | US | disclosed |
| CN-112513025-A | Chemical process for the preparation of phenylpiperidinylindole derivatives | 诺华股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102718692-A | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169630-A1 | CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES | IDO1, CYP3A7, PAH | NSD2 2259/4885ABL1 149/4885PPARG 1895/4885 |
| US-11208398-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | CYP3A7, CYP3A5, IDO1 | NSD2 2307/4885ABL1 151/4885PPARG 1798/4885 |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | NSD2 1003/4885ABL1 2352/4885PPARG 552/4885 |
| US-11578053-B2 | Chemical process for preparing phenylpiperidinyl indole derivatives | IDO1, CYP3A7, PAH | NSD2 2259/4885ABL1 149/4885PPARG 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.