⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294074 | 0.80 | CA2 (0.37) | — | |
| SCHEMBL7520252 | 0.67 | — | — | |
| SCHEMBL15695591 | 0.54 | PDE2A (0.34) | — | |
| SCHEMBL13279077 | 0.51 | — | — | |
| SCHEMBL110031 | 0.51 | MCL1 (0.38) | — | |
| SCHEMBL20963080 | 0.51 | ALDH1A1 (0.46) | — | |
| SCHEMBL7185921 | 0.49 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL8520516 | 0.49 | MCL1 (0.36) | — | |
| SCHEMBL15119580 | 0.49 | CES1 (0.42) | — | |
| SCHEMBL24891350 | 0.47 | ELANE (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101556262-B | Method for detecting impurities in cefoxitin product | HAIKOU PHARMACEUTICAL FACTORY CO LTD | 2012-01-25 | — | — | CN | claimed |
| CN-101556262-A | Method for detecting impurities in cefoxitin product | HAIKOU PHARMACEUTICAL FACTORY (CN) | 2009-10-14 | — | — | CN | claimed |
| US-20120302547-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-8263772-B2 | MCH receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| CN-101556262-B | Method for detecting impurities in cefoxitin product | HAIKOU PHARMACEUTICAL FACTORY CO LTD | 2012-01-25 | — | — | CN | disclosed |
| US-8101764-B2 | MCH receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100016350-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2010-01-21 | — | — | US | disclosed |
| CN-101556262-A | Method for detecting impurities in cefoxitin product | HAIKOU PHARMACEUTICAL FACTORY (CN) | 2009-10-14 | — | — | CN | disclosed |
| CN-101460503-A | Novel MCH receptor antagonists | LILLY CO ELI (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101454328-A | Novel mch receptor antagonists | LILLY CO ELI (US) | 2009-06-10 | — | — | CN | disclosed |
| US-20090093456-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-04-09 | — | — | US | disclosed |
| EP-2029610-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | Eli Lilly & Company (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-2029609-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | Eli Lilly & Company (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007146758-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007146759-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |