SCHEMBL2642238

SCHEMBL2642238

OCc1cc(F)c(O)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
KDM4E B2RXH2 1/20 0.43
CASP6 P55212 1/20 0.43
MEP1B Q16820 1/20 0.42
DBH P09172 1/20 0.40
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
KIF11 P52732 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TSHR P16473 1/20 0.33
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36980 0.80 MEP1B (0.44) MEP1BDBHESR1ESR2ERN1
SCHEMBL14421368 0.80 PTGS1 (0.45) MEP1BDBHESR1ESR2
SCHEMBL391375 0.80 ACHE (0.46) ACHEKDM4ECASP6CYP4F2CYP4A11
SCHEMBL523766 0.78 ACHE (0.43) ACHEKDM4ECASP6CYP4F2CYP4A11
SCHEMBL68262 0.77 ACHE (0.55) ACHEKDM4ECASP6TSHR
SCHEMBL31296199 0.76 TTR (0.46) KDM4ECASP6
SCHEMBL6302839 0.76 MEP1B (0.41) MEP1BDBH
SCHEMBL6124950 0.76 MEP1B (0.41) KDM4EMEP1BDBH
SCHEMBL855473 0.76 ACHE (0.42) ACHEKDM4ECASP6CYP4F2CYP4A11
SCHEMBL6167933 0.76 MEP1B (0.46) MEP1BDBHESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497428-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2025-12-16 US disclosed
US-20230416460-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED PRODUCT, AND LAMINATED SUBSTRATE TDK CORPORATION (JP) 2023-12-28 US disclosed
CN-116490355-A Compound, resin composition, resin sheet, resin cured product, and laminated substrate TDK株式会社 2023-07-25 CN disclosed
US-11597702-B2 Substituted pyrazoles FFA4/GPR120 receptor agonists GOLGI NEUROSCIENCES S.R.L. (IT) 2023-03-07 US disclosed
WO-2022209495-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED OBJECT, AND LAMINATED SUBSTRATE TDK株式会社 2022-10-06 WO disclosed
US-20210380624-A1 GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2021-12-09 US disclosed
CN-113366007-A Galactoside inhibitors of galectins 格莱克特生物技术公司 2021-09-07 CN disclosed
US-20210087148-A1 SUBSTITUTED PYRAZOLES FFA4/GPR120 RECEPTOR AGONISTS GOLGI NEUROSCIENCES S.R.L. (IT) 2021-03-25 US disclosed
EP-3765446-A1 SUBSTITUTED PYRAZOLES FFA4/GPR120 RECEPTOR AGONISTS AXXAM S.p.A. (IT) 2021-01-20 EP disclosed
CN-111868035-A Substituted pyrazole FFA4/GPR120 receptor agonists 阿克萨姆股份公司 2020-10-30 CN disclosed
WO-2020078808-A1 GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2020-04-23 WO disclosed
WO-2019175152-A1 SUBSTITUTED PYRAZOLES FFA4/GPR120 RECEPTOR AGONISTS AXXAM S.P.A. (IT) 2019-09-19 WO disclosed
US-7687502-B2 Substituted quinazoline or pyridopyrimidine derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-03-30 US disclosed
US-20080032996-A1 Substituted Quinazoline or Pyridopyrimidine Derivative MSD K.K. (JP) 2008-02-07 US disclosed
EP-1734040-A1 SUBSTITUTED QUINAZOLINE OR PYRIDOPYRIMIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-12-20 EP disclosed
US-6211328-B1 IN PRESENCE OF AN ACID GUN EI CHEMICAL INDUSTRY CO., LTD (JP) 2001-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210087148-A1 SUBSTITUTED PYRAZOLES FFA4/GPR120 RECEPTOR AGONISTS FFAR4, FFAR3, FFAR1 ACHE 4485/4885KDM4E 3733/4885CASP6 3595/4885
US-20210380624-A1 GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS2 ACHE 2494/4885KDM4E 4680/4885CASP6 2244/4885
US-12497428-B2 Galactoside inhibitor of galectins LGALS1, LGALS3, LGALS2 ACHE 2494/4885KDM4E 4680/4885CASP6 2244/4885
US-11597702-B2 Substituted pyrazoles FFA4/GPR120 receptor agonists FFAR4, FFAR3, FFAR1 ACHE 4485/4885KDM4E 3733/4885CASP6 3595/4885
US-20080032996-A1 Substituted Quinazoline or Pyridopyrimidine Derivative GCK, GCKR, PDXK ACHE 2031/4885KDM4E 1277/4885CASP6 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.