Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 5/20 | 0.37 |
| ▸ | CDK9 | P50750 | 5/20 | 0.37 |
| ▸ | SAT1 | P21673 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HOGA1 | Q86XE5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773094 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4349285 | 0.84 | SAT1 (0.47) | ALDH1A1TSHRTDP1SAT1ATM | |
| SCHEMBL7946281 | 0.80 | ADH1B (0.42) | ALDH1A1TSHRTDP1SAT1ATM | |
| SCHEMBL4962562 | 0.78 | SAT1 (0.45) | SAT1NPC1RAB9ACHRM2CHRM1 | |
| SCHEMBL5360130 | 0.76 | KCNH3 (0.37) | ALDH1A1TDP1SAT1NPC1RAB9A | |
| SCHEMBL16086929 | 0.74 | SAT1 (0.55) | ALDH1A1TSHRSAT1GNAI3GNAO1 | |
| SCHEMBL14613735 | 0.73 | CHRM2 (0.33) | KDM1ACHRM2CHRM1CHRM3 | |
| SCHEMBL4572204 | 0.73 | SAT1 (0.48) | SAT1NPC1RAB9AGNAI3GNAO1 | |
| SCHEMBL5012078 | 0.72 | KDM4E (0.39) | ALDH1A1TDP1CCNKCDK9CCNT1 | |
| SCHEMBL19087023 | 0.72 | GNAI3 (0.62) | ALDH1A1TSHRSAT1KMT2AGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035372-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2008005338-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | claimed |
| US-20150011759-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011759-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | TPMT, SPR, QDPR | ALDH1A1 1386/4885TSHR 2339/4885TDP1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.