Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136913 | 0.75 | CYP2E1 (0.39) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL7219105 | 0.72 | CYP2E1 (0.49) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL798353 | 0.72 | CYP2E1 (0.41) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL6472029 | 0.71 | CYP2E1 (0.48) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL11385986 | 0.69 | NAAA (0.41) | HTT | |
| SCHEMBL31421458 | 0.69 | CYP2D6 (0.47) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL6626248 | 0.69 | CYP2E1 (0.59) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL3280017 | 0.68 | NCOA3 (0.42) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL846286 | 0.67 | GPR119 (0.44) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL2982329 | 0.65 | HTR6 (0.48) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013220-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | Archimica GmbH (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121805-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | ARCHIMICA GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |