Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL602419 | 0.81 | SLC22A12 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2258374 | 0.81 | ACP3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL2260403 | 0.78 | PTPN5 (0.35) | — | |
| Hydrochloric Acid SCHEMBL2462166 | 0.78 | IMPDH2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL2264053 | 0.76 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2260155 | 0.73 | ALDH1A1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL3922779 | 0.72 | ACP3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2259707 | 0.72 | NPC1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL3922785 | 0.72 | RAB9A (0.36) | — | |
| Hydrochloric Acid SCHEMBL3921996 | 0.72 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | claimed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | claimed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | claimed |
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-7567371-B2 | Electrochromic compounds | NTERA LIMITED (IE) | 2009-07-28 | — | — | US | disclosed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | disclosed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | disclosed |