Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 3/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23291825 | 0.89 | SIRT3 (0.47) | ICAM1SELEVCAM1SIRT3TDP1 | |
| SCHEMBL392397 | 0.80 | TSHR (0.48) | TDP1CYP3A4KMT2ACASP1LMNA | |
| SCHEMBL3223706 | 0.80 | TSHR (0.34) | ICAM1SELEVCAM1CYP3A4 | |
| SCHEMBL2760647 | 0.79 | ICAM1 (0.41) | ICAM1SELEVCAM1SIRT3TDP1 | |
| SCHEMBL19250641 | 0.79 | SIRT3 (0.40) | ICAM1SELEVCAM1SIRT3TDP1 | |
| SCHEMBL1703067 | 0.75 | ICAM1 (0.47) | ICAM1SELEVCAM1SIRT3NNMT | |
| Hydrochloric Acid SCHEMBL5010437 | 0.73 | ICAM1 (0.46) | ICAM1SELEVCAM1SIRT3NNMT | |
| SCHEMBL651312 | 0.72 | SIRT3 (0.60) | SIRT3TDP1NNMTMKNK1MKNK2 | |
| SCHEMBL826357 | 0.72 | MKNK1 (0.58) | SIRT3TDP1NNMTMKNK1MKNK2 | |
| SCHEMBL5872058 | 0.72 | P2RX7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602041-A1 | HPK1 INHIBITORS AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024081385-A1 | HPK1 INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| US-20170318816-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2017-11-09 | — | — | US | disclosed |
| US-9743674-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2016-10-13 | — | — | US | disclosed |
| US-9392797-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150264939-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2015-09-24 | — | — | US | disclosed |
| US-9078447-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2015-07-14 | — | — | US | disclosed |
| EP-2665725-A1 | BICYCLIC INHIBITORS OF ALK | AbbVie Inc. (US) | 2013-11-27 | — | — | EP | disclosed |
| US-8410142-B2 | Bipyridine carboxamide orexin receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-04-02 | — | — | US | disclosed |
| US-7632865-B2 | Thioamides and salts thereof and cytokine production inhibitors containing both | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20090197929-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds | BASF SE (DE) | 2009-08-06 | — | — | US | disclosed |
| WO-2009063076-A2 | FUNGICIDAL MIXTURES III | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| EP-2003973-A2 | ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008108991-A1 | BIPYRIDINE CARBOXAMIDE OREXIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| EP-1885712-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2007112893-A2 | ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2007-10-11 | — | — | WO | disclosed |
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | ISHIHARA SANGYO KAISHA, LTD (JP) | 2007-09-20 | — | — | US | disclosed |
| WO-2006122955-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
| US-6403587-B1 | AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND | PFIZER INC. | 2002-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197929-A1 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds | CBR3, PPOX, CBR1 | ICAM1 3864/4885SELE 4884/4885VCAM1 4819/4885 |
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | IFNG, TST, STAT6 | ICAM1 1010/4885SELE 1943/4885VCAM1 1219/4885 |
| US-20170318816-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | O60361, SPOUT1, FBL | ICAM1 4841/4885SELE 4842/4885VCAM1 4860/4885 |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | O60361, SPOUT1, FBL | ICAM1 4812/4885SELE 4758/4885VCAM1 4842/4885 |
| US-20150264939-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | O60361, SPOUT1, FBL | ICAM1 4812/4885SELE 4758/4885VCAM1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.