SCHEMBL3925541

SCHEMBL3925541

ClC(Cl)(Cl)c1c[c]cc(C(Cl)(Cl)Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596645 0.84 TSHR (0.31) TSHR
SCHEMBL1538847 0.75 TSHR (0.47) TSHR
SCHEMBL7297017 0.71
SCHEMBL5951815 0.71
SCHEMBL102848 0.69 CES2 (0.40) TSHR
Magnesium Chloride Anhydrous SCHEMBL27957567 0.67 GABRA1 (0.39)
SCHEMBL68480 0.67 TSHR (0.55) TSHR
SCHEMBL23174652 0.67 CES2 (0.39) TSHR
SCHEMBL3519407 0.67 TSHR (0.35) TSHR
SCHEMBL27477402 0.67 GABRA1 (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108398474-A It is a kind of to can be used for the electric potential type microelectrode sensors and its application that deposit intermediate ion detects 中国科学院烟台海岸带研究所 2018-08-14 CN claimed
US-6509426-B2 Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability JAPAN POLYCHEM CORPORATION (JP) 2003-01-21 US claimed
WO-2020130592-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 서울대학교산학협력단 2020-06-25 WO disclosed
CN-109799681-A A kind of positive-working lithographic printing plate precursor of Uv and visible light sensitivity and the method for forming image 浙江康尔达新材料股份有限公司 2019-05-24 CN disclosed
CN-108957951-A Photosensitive polymer combination, photo-sensitive resin and colour filter using it 三星SDI株式会社 2018-12-07 CN disclosed
CN-108398474-A It is a kind of to can be used for the electric potential type microelectrode sensors and its application that deposit intermediate ion detects 中国科学院烟台海岸带研究所 2018-08-14 CN disclosed
CN-107449815-A It is a kind of available for the electric potential type microelectrode sensors of Single cell analysis and its application 中国科学院烟台海岸带研究所 2017-12-08 CN disclosed
US-7517828-B2 Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst TOAGOSEI CO., LTD. (JP) 2009-04-14 US disclosed
US-20060276329-A1 Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst TOAGOSEI CO., LTD. (JP) 2006-12-07 US disclosed
EP-1623971-A1 ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST TOAGOSEI CO., LTD. (JP) 2006-02-08 EP disclosed
US-6538161-B2 Naphthalene skeleton substituted with a 1- or 2- position electron donating group and a 6- or 4- position electron attractive group; emitts visible light with a desired color by choosing appropriate combinations TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-25 US disclosed
US-6509426-B2 Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability JAPAN POLYCHEM CORPORATION (JP) 2003-01-21 US disclosed
US-20020156319-A1 Fluorescent compounds HIROSE ENGINEERING CO., LTD. (JP) 2002-10-24 US disclosed
US-20010023296-A1 Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer JAPAN POLYCHEM CORPORATION (JP) 2001-09-20 US disclosed
EP-1127934-A1 Ultraviolet crosslinking pressure-sensitive adhesive composition, process for producing same, pressure-sensitive adhesive sheet and process for producing same NITTO DENKO CORPORATION (JP) 2001-08-29 EP disclosed
US-6218558-B1 BRIDGED OXYGEN-, NITROGEN- OR SULFUR-CONTAINING METALLOCENE CATALYST CONTAINING AT LEAST CYCLOPENTADIENE RING FUSED TO A C7-10 RING JAPAN POLYCHEM CORPORATION (JP) 2001-04-17 US disclosed
EP-0963996-A2 Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer Japan Polychem Corporation (JP) 1999-12-15 EP disclosed
EP-0275501-B1 PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS BASF Aktiengesellschaft (DE) 1991-03-06 EP disclosed
US-4837356-A Process for the preparation of alkyl 4-ketoalkanoates SHELL OIL COMPANY (US) 1989-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023296-A1 Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer OSTC, TCP1, COG1 TSHR 4771/4885
US-20060276329-A1 Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst LSS, COASY, FASN TSHR 3114/4885
US-20020156319-A1 Fluorescent compounds NES, NDC1, DYNC1LI2 TSHR 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.