SCHEMBL3926952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3920468	0.89	HSD11B1 (0.46)	GAATSHRHTTSMN1; SMN2CCR5
	SCHEMBL3919295	0.83	KMT2A (0.45)	TSHRHTTCCR5MEN1KMT2A
	SCHEMBL3925589	0.83	MEN1 (0.44)	GAASMN1; SMN2CCR5MEN1KMT2A
	SCHEMBL3918743	0.80	ALDH1A1 (0.38)	GAATSHRHTTSMN1; SMN2HSD11B1
	SCHEMBL3915453	0.79	HSD11B1 (0.48)	GAATSHRHTTSMN1; SMN2HSD11B1
	SCHEMBL3917724	0.78	CYP2D6 (0.51)	GAATSHRHTTSMN1; SMN2MEN1
	SCHEMBL3925408	0.78	SMN1; SMN2 (0.48)	GAATSHRHTTSMN1; SMN2MEN1
	SCHEMBL4034055	0.78	L3MBTL1 (0.45)	GAATSHRHTTMEN1KMT2A
	SCHEMBL4041277	0.77	KMT2A (0.41)	GAATSHRHTTSMN1; SMN2HSD11B1
	SCHEMBL3919576	0.77	MMP2 (0.51)	GAATSHRHTTSMN1; SMN2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.