Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197929 | 0.84 | MEN1 (0.44) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3483258 | 0.83 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL227330 | 0.81 | MAOA (0.55) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1777148 | 0.81 | MAPT (0.35) | KMT2ASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL17400963 | 0.81 | SLC6A4 (0.37) | SLC6A4TDP1L3MBTL1TSHR | |
| SCHEMBL2040029 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12135641 | 0.81 | MAOA (0.52) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL23422564 | 0.80 | MEN1 (0.39) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17400964 | 0.80 | APP (0.44) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL7867405 | 0.80 | EPHX1 (0.40) | SLC6A2SLC6A4SLC6A3MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9373794-B2 | Phosphorescent compounds and organic light emitting diode devices using the same | LG DISPLAY CO., LTD. (KR) | 2016-06-21 | — | — | US | disclosed |
| US-20140175406-A1 | PHOSPHORESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE DEVICES USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2014-06-26 | — | — | US | disclosed |
| US-20140175406-A1 | PHOSPHORESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE DEVICES USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2014-06-26 | — | — | US | disclosed |
| US-8546358-B2 | Method of treating asthma | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-01 | — | — | US | disclosed |
| US-20120022022-A1 | NOVEL INHIBITORS OF CHYMASE | HAWKINS MICHAEL J (US) | 2012-01-26 | — | — | US | disclosed |
| US-20100048513-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2010-02-25 | — | — | US | disclosed |
| US-20100048513-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2010-02-25 | — | — | US | disclosed |
| EP-2044061-A2 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | Kahraman, Mehmet (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20090036409-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2009-02-05 | — | — | US | disclosed |
| US-20090036409-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2009-02-05 | — | — | US | disclosed |
| US-7459444-B2 | Inhibitors of chymase | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-02 | — | — | US | disclosed |
| US-7459444-B2 | Inhibitors of chymase | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-02 | — | — | US | disclosed |
| WO-2008011560-A2 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | KAHRAMAN MEHMET (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008011560-A2 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | KAHRAMAN MEHMET (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | Kahraman, Mehmet (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | Kahraman, Mehmet (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | Kahraman, Mehmet (US) | 2008-01-24 | — | — | US | disclosed |
| WO-2005073214-A2 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048513-A1 | Novel inhibitors of chymase | CMA1, SERPINB1, TPSAB1 | MEN1 1894/4885KMT2A 4119/4885SLC6A2 3939/4885 |
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | RHOT2, ROCK2, ROCK1 | MEN1 4196/4885KMT2A 2808/4885SLC6A2 2752/4885 |
| US-20090036409-A1 | Novel inhibitors of chymase | CMA1, SERPINB1, TPSAB1 | MEN1 1894/4885KMT2A 4119/4885SLC6A2 3939/4885 |
| US-20120022022-A1 | NOVEL INHIBITORS OF CHYMASE | CMA1, SERPINB1, TPSAB1 | MEN1 1894/4885KMT2A 4119/4885SLC6A2 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.