Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162477 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL283203 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL27442149 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL30396748 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL6017915 | 0.84 | RARB (0.55) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL7840274 | 0.83 | CES2 (0.50) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL645757 | 0.83 | ALDH1A1 (0.54) | SMN1; SMN2TSHRCASP1ALDH1A1TP53 | |
| SCHEMBL911253 | 0.81 | DGAT1 (0.60) | SMN1; SMN2TSHRCASP1ALDH1A1CYP11B2 | |
| SCHEMBL29392929 | 0.81 | MAOB (0.58) | SMN1; SMN2TSHRCASP1ALDH1A1CYP11B2 | |
| SCHEMBL325429 | 0.81 | MAOB (0.58) | SMN1; SMN2TSHRCASP1ALDH1A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666668-A | Synthesis method of pain medicine synthesis building block 4, 5-dichloro-2-fluorobenzoic acid in clinical research | 上海苏博医药科技有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-115043833-A | Bcl-2 fluorescent probe and preparation method and application thereof | 山东大学 | 2022-09-13 | — | — | CN | claimed |
| CN-110724050-B | Refining method of 2-chloro-6-fluorobenzoic acid | 浙江大洋生物科技集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-111689881-B | Synthetic method of azosemide intermediate | 苏州华道生物药业股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | claimed |
| EP-3551633-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2021-03-31 | — | — | EP | claimed |
| CN-111689881-A | Synthetic method of azosemide intermediate | 苏州华道生物药业股份有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111518055-A | Preparation method of benzothiazepine oxide, product prepared by preparation method and application of product | 西安都创医药科技有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-110818556-A | Method for producing high-purity 2-chloro-6-fluorobenzoyl chloride by using waste residues | 浙江大洋生物科技集团股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110724050-A | Refining method of 2-chloro-6-fluorobenzoic acid | 浙江大洋生物科技集团股份有限公司 | 2020-01-24 | — | — | CN | claimed |
| EP-3551633-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | claimed |
| CN-106986789-B | Hydroquinone compound and preparation method thereof and the application in antitumor or immunological regulation | 中国人民解放军军事医学科学院生物医学分析中心 | 2019-07-16 | — | — | CN | claimed |
| WO-2018108230-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2018-06-21 | — | — | WO | claimed |
| CN-106986789-A | Hydroquinone compound and preparation method thereof and the application in antitumor or immunological regulation | 中国人民解放军军事医学科学院生物医学分析中心 | 2017-07-28 | — | — | CN | claimed |
| US-20110260051-A1 | METHOD FOR DETECTING TRACER COMPOUNDS FOR HYDROCARBON PRODUCTION | TOTAL S.A. (FR) | 2011-10-27 | — | — | US | claimed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| US-20040204454-A1 | Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | claimed |
| US-20260144252-A1 | BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND THEIR SALTS, AGENTS FOR PROTECTING USEFUL PLANTS OR CROP PLANTS COMPRISING THEM, METHODS FOR PRODUCING THEM AND THEIR USE AS SAFENERS | BAYER AKTIENGESELLSCHAFT (DE) | 2026-05-28 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144252-A1 | BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND THEIR SALTS, AGENTS FOR PROTECTING USEFUL PLANTS OR CROP PLANTS COMPRISING THEM, METHODS FOR PRODUCING THEM AND THEIR USE AS SAFENERS | CBR3, CBR1, CA3 | SMN1; SMN2 3105/4885TSHR 385/4885CASP1 724/4885 |
| US-20040204454-A1 | Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors | PEPD, TFPI, F2 | SMN1; SMN2 3010/4885TSHR 2279/4885CASP1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.