SCHEMBL3929903

SCHEMBL3929903

COc1ccccc1[C@H](C)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA14 Q9ULX7 1/20 0.55
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
AGTR1 P30556 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
ACHE P22303 1/20 0.47
KMT2A Q03164 1/20 0.47
ENPP2 Q13822 1/20 0.46
POLB P06746 2/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14376164 1.00 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL30010698 1.00 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL4609960 1.00 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL343860 1.00 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL6180225 0.88 CA1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL4440523 0.86 P2RX3 (0.42) AGTR1LMNACYP1A2ACHEKMT2A
SCHEMBL5667375 0.86 APP (0.46) CA1CA2CA7CA9CA12
SCHEMBL7259231 0.85 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL23084671 0.83 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL238441 0.83 CA1 (0.57) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115209993-A Catalyst comprising activated carbon having ruthenium complex adsorbed thereon and method for producing reduced product using same 高砂香料工业株式会社 2022-10-18 CN disclosed
CN-113260623-A Manganese catalysts and their use in the hydrogenation of ketones 圣安德鲁斯大学董事会 2021-08-13 CN disclosed
CN-105087666-A Method for producing (S)-methoxyphenyl ethanol by use of yeast UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-25 CN disclosed
US-7638628-B2 for the reduction of ketones to alcohols via hydrogen transfer; reduction catalysts; hydrogenation catalysts UNIVERSITA' DEGLI STUDI DI UDINE (IT) 2009-12-29 US disclosed
EP-1934159-B1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2009-03-25 EP disclosed
US-20090030235-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2009-01-29 US disclosed
US-20080249308-A1 Complexes of Ruthenium with 2-(Aminomethyl)Pyridines and Phosphines, their Preparation and Use as Catalysts UNIVERSITA'DEGLI STUDI DI UDINE (IT) 2008-10-09 US disclosed
EP-1747224-B1 COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2008-07-16 EP disclosed
CN-100398626-C Method for increasing helical twist rate, optically active compound, liquid crystal composition containing the same, and liquid crystal display element DAINIPPON INK & CHEMICALS (JP) 2008-07-02 CN disclosed
EP-1934159-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2008-06-25 EP disclosed
WO-2007036570-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2007-04-05 WO disclosed
EP-1747224-A1 COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS Universita' Degli Studi di Udine (IT) 2007-01-31 EP disclosed
WO-2005105819-A1 COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE (IT) 2005-11-10 WO disclosed
CN-1495246-A Method for increasing helical twist rate, optically active compound, liquid crystal composition containing the same, and liquid crystal display element 大日本油墨化学工业株式会社 2004-05-12 CN disclosed
US-6365398-B1 REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE BASF AKTIENGESELLSCHAFT (DE) 2002-04-02 US disclosed
EP-1031629-A2 Method of preparation of stereoisomeric carboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2000-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249308-A1 Complexes of Ruthenium with 2-(Aminomethyl)Pyridines and Phosphines, their Preparation and Use as Catalysts ADH5, PDK2, PDK1 CA1 2884/4885CA2 1715/4885CA7 1840/4885
US-20090030235-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS ADH5, ADH1C, ADH1A CA1 690/4885CA2 3431/4885CA7 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.