Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874875 | 0.84 | ADORA3 (0.46) | ADORA3HTR2AHTR7OPRM1SIGMAR1 | |
| SCHEMBL7874873 | 0.84 | ADORA3 (0.46) | ADORA3HTR2AHTR7OPRM1SIGMAR1 | |
| SCHEMBL7874870 | 0.84 | ADORA3 (0.46) | ADORA3HTR2AHTR7OPRM1SIGMAR1 | |
| SCHEMBL19100844 | 0.83 | L3MBTL1 (0.47) | L3MBTL1CTSKTSHRALDH1A1TDP1 | |
| SCHEMBL19992035 | 0.80 | SMN1; SMN2 (0.51) | HTR2ASIGMAR1CTSKALDH1A1CYP3A4 | |
| SCHEMBL1573158 | 0.79 | JAK2 (0.46) | GAA | |
| SCHEMBL1573262 | 0.79 | JAK2 (0.46) | GAA | |
| SCHEMBL8527336 | 0.78 | SIGMAR1 (0.51) | ADORA3HTR2AHTR7OPRM1SIGMAR1 | |
| SCHEMBL18498621 | 0.77 | LMNA (0.56) | L3MBTL1TSHRALDH1A1TDP1BCHE | |
| SCHEMBL8707514 | 0.76 | SMN1; SMN2 (0.55) | HTR2ASIGMAR1CTSKALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590360-A4 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES | IND RES LTD (NZ) | 2009-06-24 | — | — | EP | disclosed |
| EP-1590360-A1 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069856-A1 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2004-08-19 | — | — | WO | disclosed |