Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503604 | 0.87 | OPRD1 (0.48) | SIGMAR1OPRM1HTR2AADORA3HTR7 | |
| SCHEMBL7985869 | 0.81 | SIGMAR1 (0.50) | SIGMAR1OPRM1 | |
| SCHEMBL7985865 | 0.81 | SIGMAR1 (0.50) | SIGMAR1OPRM1 | |
| SCHEMBL3932037 | 0.78 | PPARG (0.45) | SIGMAR1OPRM1HTR2AADORA3HTR7 | |
| SCHEMBL30199385 | 0.77 | HTR2C (0.51) | SIGMAR1OPRM1HTR2AHTR1AHRH1 | |
| SCHEMBL30199508 | 0.76 | HTR2C (0.50) | SIGMAR1OPRM1HTR2AHTR1AHRH1 | |
| SCHEMBL20224788 | 0.75 | GAA (0.39) | L3MBTL1ALDH1A1TSHR | |
| SCHEMBL30199651 | 0.74 | HTR2C (0.53) | SIGMAR1HTR2AHTR1AHRH1ALDH1A1 | |
| SCHEMBL31679608 | 0.74 | HTR2C (0.46) | SIGMAR1OPRM1HTR2AHTR1AHRH1 | |
| SCHEMBL7874873 | 0.74 | ADORA3 (0.46) | SIGMAR1OPRM1HTR2AADORA3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |