Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL303703 | 0.91 | CYP2A6 (0.40) | CYP2A6ALOX12CYP17A1CYP19A1CYP11B1 | |
| Pyridine SCHEMBL23294750 | 0.87 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28304620 | 0.87 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL339405 | 0.87 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Anthracene SCHEMBL27585398 | 0.83 | ALDH1A1 (0.37) | TDP1CYP2A6ALOX12CYP17A1CYP19A1 | |
| Pyridine SCHEMBL16470497 | 0.80 | TSHR (0.43) | TSHRNAPRTTDP1 | |
| Benzene SCHEMBL28323090 | 0.80 | TSHR (0.43) | TSHRNAPRTTDP1 | |
| Biphenyl SCHEMBL2199525 | 0.80 | NOTUM (0.50) | TSHRNOTUMCYP2A6CYP19A1KDM4E | |
| Isoquinoline SCHEMBL29501078 | 0.80 | TNF (0.37) | CYP2A6CYP17A1CYP19A1CYP11B1CYP11B2 | |
| Isoquinoline SCHEMBL1743732 | 0.80 | TNF (0.37) | CYP2A6CYP17A1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609459-B1 | Use of polycationic compounds for dyeing keratinous fibers | OREAL (FR) | 2009-04-08 | — | — | EP | claimed |
| US-20060162098-A1 | Use of polycationic compounds for dyeing keratin fibres | L'OREAL S.A. (FR) | 2006-07-27 | — | — | US | claimed |
| US-20060162098-A1 | Use of polycationic compounds for dyeing keratin fibres | L'OREAL S.A. (FR) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162098-A1 | Use of polycationic compounds for dyeing keratin fibres | KRT18, DSG1, DSP | TSHR 4853/4885NAPRT 1748/4885TDP1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.