Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934180 | 0.87 | TDP1 (0.38) | L3MBTL1KMT2APOLBRAB9AALDH1A1 | |
| SCHEMBL3937178 | 0.87 | NFE2L2 (0.46) | L3MBTL1KMT2APOLBRAB9AALDH1A1 | |
| SCHEMBL3934665 | 0.82 | KMT2A (0.47) | L3MBTL1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL1399110 | 0.78 | F2R (0.46) | L3MBTL1KMT2APOLBNFE2L2MEN1 | |
| SCHEMBL3943715 | 0.78 | ALDH1A1 (0.44) | L3MBTL1KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1399112 | 0.78 | F2R (0.46) | L3MBTL1KMT2APOLBNFE2L2MEN1 | |
| SCHEMBL3945177 | 0.69 | MAPT (0.49) | KMT2APOLBALDH1A1MEN1KDM4E | |
| SCHEMBL3935366 | 0.68 | F2R (0.45) | KMT2AMEN1 | |
| SCHEMBL3935485 | 0.68 | ALDH1A1 (0.54) | L3MBTL1KMT2ARAB9AALDH1A1MEN1 | |
| SCHEMBL8828323 | 0.68 | PAM (0.58) | RAB9ANFE2L2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046748-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | Pierre Fabre Medicament (FR) | 2009-04-15 | — | — | EP | claimed |
| WO-2007147822-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2007-12-27 | — | — | WO | claimed |