Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.48 |
| ▸ | LAP3 | P28838 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496511 | 0.97 | FDPS (0.50) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL3936724 | 0.97 | FDPS (0.50) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL4436425 | 0.81 | FDPS (0.42) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5059565 | 0.77 | FDPS (0.46) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL6663397 | 0.77 | FDPS (0.38) | FDPSLAP3LMNA | |
| SCHEMBL7511455 | 0.75 | LMNA (0.45) | FDPSLAP3LMNAALDH1A1 | |
| SCHEMBL16091906 | 0.72 | FDPS (0.52) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5318557 | 0.70 | FDPS (0.46) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5489929 | 0.70 | LAP3 (0.46) | FDPSLAP3LMNAMETAP1ADRB3 | |
| SCHEMBL6132043 | 0.70 | LAP3 (0.46) | FDPSLAP3LMNAMETAP1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848728-A1 | IBANDRONATE POLYMORPH A | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006081963-A1 | IBANDRONATE POLYMORPH A | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |