Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496511 | 0.79 | FDPS (0.50) | FDPSLMNALAP3 | |
| SCHEMBL3936724 | 0.79 | FDPS (0.50) | FDPSLMNALAP3 | |
| SCHEMBL5572484 | 0.77 | FDPS (0.48) | FDPSLMNALAP3 | |
| SCHEMBL8588658 | 0.75 | GABRR1 (0.32) | FDPSLMNA | |
| SCHEMBL8619867 | 0.73 | GABBR2 (0.33) | FDPSLMNA | |
| SCHEMBL4436425 | 0.69 | FDPS (0.42) | FDPSLMNALAP3 | |
| SCHEMBL13976468 | 0.67 | LMNA (0.36) | FDPSLMNA | |
| SCHEMBL5059565 | 0.66 | FDPS (0.46) | FDPSLMNALAP3 | |
| SCHEMBL5318557 | 0.65 | FDPS (0.46) | FDPSLMNALAP3 | |
| SCHEMBL20892916 | 0.64 | LAP3 (0.37) | FDPSLMNALAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |