Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980638 | 0.83 | EPHX1 (0.55) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL3936610 | 0.81 | KMT2A (0.41) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL27147272 | 0.81 | HSD11B1 (0.61) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL30807383 | 0.81 | HSD11B1 (0.61) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL8534730 | 0.78 | SMN1; SMN2 (0.49) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL1816549 | 0.78 | KDM4E (0.50) | KMT2AMEN1L3MBTL1THRBATM | |
| SCHEMBL19002609 | 0.77 | EPHX2 (0.54) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL30711979 | 0.77 | KMT2A (0.39) | KMT2AMEN1HSD11B1L3MBTL1THRB | |
| SCHEMBL27877748 | 0.76 | EPHX2 (0.43) | KMT2AMEN1ALDH1A1POLBEPHX2 | |
| SCHEMBL28539475 | 0.76 | ITGB3 (0.49) | KMT2AL3MBTL1THRBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |