Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ATF4 | P18848 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977632 | 0.82 | EPHX1 (0.56) | KMT2AMEN1FAAHHSD11B1EPHX2 | |
| SCHEMBL3937465 | 0.81 | KMT2A (0.46) | KMT2AMEN1HSD11B1EPHX2THRB | |
| SCHEMBL30711979 | 0.78 | KMT2A (0.39) | KMT2AMEN1HSD11B1EPHX2THRB | |
| SCHEMBL27877748 | 0.77 | EPHX2 (0.43) | KMT2AMEN1EPHX2ALDH1A1EPHX1 | |
| SCHEMBL8534730 | 0.77 | SMN1; SMN2 (0.49) | KMT2AMEN1HSD11B1EPHX2THRB | |
| Hydrochloric Acid SCHEMBL2967152 | 0.76 | GNAI3 (0.47) | KMT2AMEN1EPHX2EPHX1NPSR1 | |
| SCHEMBL5239781 | 0.74 | FAAH (0.47) | FAAHTHRBATML3MBTL1ALDH1A1 | |
| SCHEMBL30807383 | 0.73 | HSD11B1 (0.61) | KMT2AMEN1HSD11B1THRBATM | |
| SCHEMBL27147272 | 0.73 | HSD11B1 (0.61) | KMT2AMEN1HSD11B1THRBATM | |
| SCHEMBL6187601 | 0.72 | CTSK (0.56) | HSD11B1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |