Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941453 | 0.88 | BCL9 (0.47) | DRD2DRD3KMT2ABCL9CTNNB1 | |
| SCHEMBL3939587 | 0.88 | DRD3 (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL3930618 | 0.88 | ALDH1A1 (0.53) | KMT2ABCL9CTNNB1ALDH1A1TSHR | |
| SCHEMBL3939609 | 0.86 | DRD3 (0.45) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL3940272 | 0.86 | ALDH1A1 (0.50) | DRD2DRD3KMT2ADRD1DRD4 | |
| SCHEMBL3936397 | 0.86 | DRD2 (0.45) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL3936472 | 0.85 | TP53 (0.48) | KMT2ABCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL3941279 | 0.85 | BCL9 (0.46) | KMT2ABCL9CTNNB1TSHRMEN1 | |
| SCHEMBL3941513 | 0.85 | SMN1; SMN2 (0.48) | KMT2ABCL9CTNNB1MEN1 | |
| SCHEMBL3935876 | 0.85 | BCL9 (0.50) | KMT2ABCL9CTNNB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |