Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 9/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751486 | 0.76 | NPSR1 (0.42) | CNR2 | |
| SCHEMBL3392295 | 0.72 | ALDH1A1 (0.36) | HCAR2HCAR3TSHRDAOGABRA1 | |
| SCHEMBL18798818 | 0.71 | FABP3 (0.37) | HCAR2FABP3FABP4ALOX15TSHR | |
| SCHEMBL24912696 | 0.69 | HCAR2 (0.40) | HCAR2HCAR3FABP3FABP4ACE2 | |
| SCHEMBL16011538 | 0.68 | GABRA1 (0.42) | HCAR2FABP3FABP4TSHRGABRA1 | |
| SCHEMBL27087494 | 0.68 | HCAR2 (0.61) | HCAR2HCAR3DAO | |
| SCHEMBL26136942 | 0.66 | KEAP1 (0.50) | FABP3FABP4GABRA1GABRB1EIF4A3 | |
| SCHEMBL23808984 | 0.66 | ALOX15 (0.58) | ALOX15TSHR | |
| SCHEMBL28111753 | 0.65 | GABRA1 (0.35) | FABP3FABP4CNR2GABRA1GABRB1 | |
| SCHEMBL28111741 | 0.65 | SYK (0.36) | FABP3FABP4CNR2GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020603-A9 | UPP AMPHIPHILIC ALPHA-HELIX MIMETICS | SCRIPPS RESEARCH INST (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009020603-A2 | UPP AMPHIPHILIC ALPHA-HELIX MIMETICS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-12 | — | — | WO | disclosed |