SCHEMBL394287

SCHEMBL394287

Cc1cc(=O)n(-c2ccc(C(=O)O)cc2)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
KMT2A Q03164 6/20 1.00
MAPT P10636 5/20 1.00
KDM4E B2RXH2 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
GAA P10253 4/20 0.68
MEN1 O00255 4/20 0.68
HTT P42858 3/20 0.68
LMNA P02545 2/20 0.59
RECQL P46063 1/20 0.59
KDM5A P29375 1/20 0.58
KDM2B Q8NHM5 1/20 0.58
KDM4C Q9H3R0 1/20 0.58
ALKBH5 Q6P6C2 8/20 0.51
KAT8 Q9H7Z6 1/20 0.48
ENPP3 O14638 2/20 0.47
ALPL P05186 2/20 0.47
XIAP P98170 2/20 0.47
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894742 0.83 ALDH1A1 (0.70) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL29094080 0.83 ALDH1A1 (0.70) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL693015 0.81 ALKBH5 (0.73) ALDH1A1KMT2AMAPTKDM4ETDP1
Methyl Alcohol SCHEMBL1028813 0.81 MAPT (0.69) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL28264294 0.81 MAPT (1.00) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL11589085 0.81 ALDH1A1 (0.68) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL34121 0.80 ALDH1A1 (0.68) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL5425653 0.80 ALDH1A1 (0.68) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL486125 0.80 MAPT (0.73) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL9150171 0.80 ALDH1A1 (0.68) ALDH1A1KMT2AMAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924990-A Isotope-labeled-based 1- (4-esterphenyl) -3-methyl-5-pyrazolone reagent and synthetic method and application thereof 郑州大学 2023-10-24 CN claimed
CN-109824740-B Method for interconversion between different pyrazolone reagent derivatives of reducing sugars 西北大学 2023-03-10 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
EP-2421613-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP claimed
US-7985266-B2 Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-07-26 US claimed
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof NOXELL CORPORATION 2011-02-17 US claimed
WO-2010123866-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US disclosed
CN-119224174-A Disaccharide isomer analysis reagent and analysis method thereof 常州华班亚生物科技有限公司 2024-12-31 CN disclosed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP disclosed
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2023-12-28 US disclosed
CN-117222397-A Granular hair dyeing composition 威娜德国有限责任公司 2023-12-12 CN disclosed
EP-3512488-B1 HAIR COLOR COMPOSITIONS COMPRISING STABLE VIOLET-BLUE TO BLUE IMIDAZOLIUM DYES WELLA OPERATIONS US LLC (US) 2023-12-06 EP disclosed
US-4560744-A FOR NYLON AND NATURAL POLYAMIDES BASF AKTIENGESELLSCHAFT (DE) 1985-12-24 US disclosed
US-4489002-A Azo compound and an azomethine compound and having a tertiary N-dative bond BASF AKTIENGESELLSCHAFT (DE) 1984-12-18 US disclosed
US-4264494-A Chromium complex dyestuffs for natural polyamides and synthetic nylons BASF AKTIENGESELLSCHAFT (DE) 1981-04-28 US disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
US-4212801-A Unsymmetrical 1:2-chromium complexes containing an azo and an azomethine bond BASF AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4052374-A UNSYMMETRICAL 1:2-CHROMIUM COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof KRT18, LPO, KRTCAP2 ALDH1A1 354/4885KMT2A 1425/4885MAPT 547/4885
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION SHH, CUTA, DSG1 ALDH1A1 2333/4885KMT2A 3273/4885MAPT 654/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 ALDH1A1 2333/4885KMT2A 3273/4885MAPT 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.