Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 17/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951472 | 0.86 | ALKBH5 (0.73) | ALKBH5ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL1942315 | 0.86 | ALKBH5 (0.63) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL11774629 | 0.85 | ALKBH5 (0.71) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL10787351 | 0.85 | ALKBH5 (0.71) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL9505312 | 0.85 | ALKBH5 (1.00) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL394287 | 0.81 | ALDH1A1 (1.00) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL7958529 | 0.81 | ALDH1A1 (0.67) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL1265504 | 0.81 | ALKBH5 (0.67) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL9196875 | 0.81 | ALDH1A1 (0.62) | ALKBH5ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL1266522 | 0.81 | ALKBH5 (0.66) | ALKBH5ALDH1A1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| US-7988740-B2 | Keratin dyeing compositions comprising a radical scavenger and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-02 | — | — | US | claimed |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | claimed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| US-20210346266-A1 | METHOD FOR DYEING A PROTEIN SUBSTRATE | ARCHROMA IP GMBH (CH) | 2021-11-11 | — | — | US | disclosed |
| EP-3846772-A1 | METHOD FOR DYEING A PROTEIN SUBSTRATE | Archroma IP GmbH (CH) | 2021-07-14 | — | — | EP | disclosed |
| CN-112512491-A | Method for dyeing protein substrates | 昂高知识产权有限公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-2830579-B1 | HAIR COLORANT COMPOSITIONS COMPRISING 3-AMINO 2,6 DIMETHYLPHENOL, METHODS, AND KITS COMPRISING THE COMPOSITIONS | NOXELL CORP (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-2830578-B1 | HAIR COLORANT COMPOSITIONS COMPRISING AMINO -2,6- DIMETHYLPHENOL AND 1,4- PHENYLENEDIAMINE-TYPE DEVELOPERS, METHODS, AND KITS COMPRISING THE COMPOSITIONS | NOXELL CORP (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-2863876-B1 | HAIR COLORANT COMPOSITIONS COMPRISING 2-METHOXYMETHYL-1,4-DIAMINOBENZENE, METHODS, AND KITS | NOXELL CORP (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-2926802-B1 | Hair colouring compositions, kits, method, and use thereof | NOXELL CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| US-9539192-B2 | Hair colouring compositions, kits, method, and use thereof | NOXELL CORPORATION (US) | 2017-01-10 | — | — | US | disclosed |
| US-20130340788-A1 | HAIR COLORANT COMPOSITIONS COMPRISING 2-METHOXYMETHYL-1,4-DIAMINOBENZENE AND 5-AMINO-4-CHLORO-O-CRESOL, METHODS, AND KITS COMPRISING THE COMPOSITIONS | WELLA OPERATIONS US, LLC | 2013-12-26 | — | — | US | disclosed |
| US-8608810-B2 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| US-20130255005-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 4-aminophenol-type developers, methods, and kits comprising the compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130255004-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7988740-B2 | Keratin dyeing compositions comprising a radical scavenger and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130255005-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 4-aminophenol-type developers, methods, and kits comprising the compositions | DDC, MSH6, DDT | ALKBH5 82/4885ALDH1A1 437/4885KMT2A 156/4885 |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | KRT18, LPO, CYB5R3 | ALKBH5 413/4885ALDH1A1 326/4885KMT2A 2020/4885 |
| US-20130255004-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | DDC, DDT, QDPR | ALKBH5 291/4885ALDH1A1 301/4885KMT2A 198/4885 |
| US-20130340788-A1 | HAIR COLORANT COMPOSITIONS COMPRISING 2-METHOXYMETHYL-1,4-DIAMINOBENZENE AND 5-AMINO-4-CHLORO-O-CRESOL, METHODS, AND KITS COMPRISING THE COMPOSITIONS | DDC, TYR, DDT | ALKBH5 58/4885ALDH1A1 230/4885KMT2A 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.