SCHEMBL3945548

SCHEMBL3945548

NS(=O)(=O)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.50
▸ DPYD Q12882 5/20 0.45
▸ MAPT P10636 3/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ ATAD2 Q6PL18 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ CYP19A1 P11511 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ THPO P40225 1/20 0.45
▸ MTOR P42345 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ HBB P68871 1/20 0.45
▸ PMP22 Q01453 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ KDM4C Q9H3R0 1/20 0.36
▸ TYMS P04818 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazole SCHEMBL8198854 0.82 GAA (0.36) GAADPYDMAPTALDH1A1ATAD2
SCHEMBL5751524 0.78 DPYD (0.45) GAADPYDMAPTALDH1A1ATAD2
SCHEMBL6684769 0.78 ATAD2 (0.50) GAADPYDMAPTALDH1A1ATAD2
SCHEMBL65085 0.67 — —
5-Bromouracil SCHEMBL29805 0.67 — —
SCHEMBL5801644 0.66 ALDH1A1 (0.64) GAADPYDMAPTALDH1A1ATAD2
SCHEMBL18783134 0.65 DPYD (0.50) GAADPYDMAPTALDH1A1ATAD2
Potassium SCHEMBL29524710 0.65 DPYD (0.50) GAADPYDMAPTALDH1A1ATAD2
Hydrochloric Acid SCHEMBL29256236 0.65 DPYD (0.50) GAADPYDMAPTALDH1A1ATAD2
SCHEMBL6573722 0.64 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 — — US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 — — EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 — — EP disclosed
CN-106543049-B Sulfamido haptens and its preparation method and the application for combining antigen 中国农业大学 2018-09-14 — — CN disclosed
CN-106543049-A The preparation method of sulfonamides hapten and its conjugated antigen and application 中国农业大学 2017-03-29 — — CN disclosed
CN-103169708-A Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds RIGEL PHARMACEUTICALS INC 2013-06-26 — — CN disclosed
WO-2009018132-A9 METHODS AND SYSTEMS FOR ATTENUATING THE TOLERANCE RESPONSE TO A DRUG NEUROVISTA CORP (US) 2009-06-25 — — WO disclosed
WO-2009018132-A2 METHODS AND SYSTEMS FOR ATTENUATING THE TOLERANCE RESPONSE TO A DRUG NEUROVISTA CORPORATION (US) 2009-02-05 — — WO disclosed
US-20090030403-A1 Methods and Systems for Attenuating the Tolerance Response to a Drug CYBERONICS, INC. 2009-01-29 — — US disclosed
CN-1625400-A 2, 4-pyrimidinediamine compounds and uses thereof RIGEL PHARMACEUTICALS INC (US) 2005-06-08 — — CN disclosed
Send feedback