Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6103834 | 0.90 | ALOX5 (0.45) | ALOX5NPBWR1MAOBMAOAALDH1A1 | |
| SCHEMBL391820 | 0.78 | RELA (0.43) | RELAALOX5MAOBMAOAALDH1A1 | |
| SCHEMBL391819 | 0.78 | RELA (0.43) | RELAALOX5MAOBMAOAALDH1A1 | |
| SCHEMBL9735984 | 0.74 | ALDH1A1 (0.53) | MCHR1NPBWR1NPSR1ALDH1A1NPC1 | |
| SCHEMBL9674148 | 0.74 | ALDH1A1 (0.53) | MCHR1NPBWR1NPSR1ALDH1A1NPC1 | |
| SCHEMBL392812 | 0.72 | MEN1 (0.41) | ALOX5MAOBNPSR1ALDH1A1HPGD | |
| SCHEMBL392811 | 0.72 | MEN1 (0.41) | ALOX5MAOBNPSR1ALDH1A1HPGD | |
| SCHEMBL23531491 | 0.70 | NPBWR1 (0.42) | MCHR1NPBWR1KMT2A | |
| SCHEMBL394998 | 0.68 | AHR (0.41) | RELAALOX5MAOBNPSR1MAOA | |
| SCHEMBL395643 | 0.68 | NFE2L2 (0.44) | ALOX5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043317-B1 | PYRIDAZINE DERIVATIVES AND MEDICAMENTS CONTAINING THEM AS ACTIVE INGREDIENT | KOWA CO (JP) | 2009-04-15 | — | — | EP | disclosed |