Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 14/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735984 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9736838 | 0.83 | HTT (0.47) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9736840 | 0.83 | HTT (0.47) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9737468 | 0.83 | HTT (0.62) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9673291 | 0.83 | HTT (0.62) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9125192 | 0.83 | RAB9A (0.54) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9125199 | 0.83 | RAB9A (0.54) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL2551062 | 0.79 | NPBWR1 (0.77) | ALDH1A1HTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL6103834 | 0.78 | ALOX5 (0.45) | ALDH1A1SMN1; SMN2MAPTNPBWR1 | |
| SCHEMBL3945846 | 0.74 | RELA (0.44) | ALDH1A1NPC1RAB9AKMT2ANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517877-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |