Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31690834 | 0.98 | DRD2 (0.49) | DRD2OPRD1OPRM1SIGMAR1CA12 | |
| SCHEMBL3946783 | 0.81 | OPRM1 (0.47) | OPRD1OPRM1CA12ALDH1A1CA2 | |
| SCHEMBL2270948 | 0.80 | OPRM1 (0.52) | DRD2OPRD1OPRM1SIGMAR1OPRK1 | |
| SCHEMBL6041772 | 0.80 | DRD2 (0.49) | DRD2OPRD1OPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL3153964 | 0.80 | OPRM1 (0.52) | DRD2OPRD1OPRM1ALDH1A1OPRK1 | |
| SCHEMBL23660784 | 0.80 | OPRD1 (0.42) | OPRD1OPRM1 | |
| SCHEMBL652461 | 0.80 | DRD2 (0.62) | DRD2OPRD1OPRM1SIGMAR1CYP3A4 | |
| SCHEMBL6601890 | 0.80 | OPRD1 (0.63) | OPRD1OPRM1OPRK1 | |
| SCHEMBL3084744 | 0.80 | OPRM1 (0.43) | OPRD1OPRM1OPRK1MEN1SLC6A2 | |
| Hydrochloric Acid SCHEMBL2585702 | 0.79 | OPRD1 (0.41) | DRD2OPRD1OPRM1CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447388-A | Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound | 南昌双天使生物科技开发有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-05-12 | — | — | US | disclosed |
| WO-2020186220-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2020-09-17 | — | — | WO | disclosed |
| EP-1097924-B1 | 4-hydroxy-4-phenylpiperidine derivatives having opioid agonist activity and pharmaceuticals containing the same | SSP CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6362203-B1 | ANALGESICS | SSP CO., LTD (JP) | 2002-03-26 | — | — | US | disclosed |
| CN-1304929-A | 4-hydroxy-4-phenyl piperidine derivative and medicine containing said derivative | SS PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |
| EP-1097924-A1 | 4-hydroxy-4-phenylpiperidine derivatives having -opioid agonist activity and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 2001-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MMP12, SLC11A2 | DRD2 4337/4885OPRD1 2755/4885OPRM1 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.