Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.66 |
| ▸ | AURKA | O14965 | 7/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | PRKCA | P17252 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.56 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210643 | 0.83 | HDAC1 (0.66) | CAMK2DGSK3BABL1PRKCABCR | |
| SCHEMBL210190 | 0.83 | ABL1 (0.76) | CAMK2DAURKAAURKBGSK3BCDK4 | |
| SCHEMBL7464657 | 0.82 | CAMK2D (0.90) | CAMK2DAURKAAURKBGSK3BCDK4 | |
| SCHEMBL3946636 | 0.82 | RAB9A (0.57) | AURKACDK2ABL1BCREGFR | |
| SCHEMBL3948017 | 0.82 | ABL1 (0.56) | CAMK2DABL1PRKCABCRCAMKK2 | |
| Hydrochloric Acid SCHEMBL7470853 | 0.82 | ABL1 (0.74) | CAMK2DAURKAAURKBGSK3BCDK4 | |
| SCHEMBL3945049 | 0.79 | CAMK2D (0.61) | CAMK2DAURKAAURKBGSK3BCDK4 | |
| SCHEMBL4062045 | 0.77 | CAMK2D (0.78) | CAMK2DAURKAAURKBGSK3BIKBKB | |
| SCHEMBL4800404 | 0.77 | MAPK8 (0.83) | CAMK2DAURKAAURKBGSK3BIKBKB | |
| SCHEMBL4712432 | 0.77 | ABL1 (0.61) | AURKAGSK3BABL1PRKCABCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922309-B1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM CO LTD (KR) | 2014-05-21 | — | — | EP | disclosed |
| US-7501424-B2 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL-YANG PHARM. CO., LTD. (KR) | 2009-03-10 | — | — | US | disclosed |
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | disclosed |
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | IL-YANG PHARM. CO., LTD. (KR) | 2008-04-24 | — | — | US | disclosed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | ITPA, TYMP, THPO | CAMK2D 2635/4885AURKA 252/4885AURKB 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.