Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958594 | 1.00 | SIGMAR1 (0.40) | SIGMAR1HTR7DRD2DRD3HTR1A | |
| SCHEMBL4763284 | 0.78 | HTR1A (0.44) | SIGMAR1HTR7DRD2DRD3HTR1A | |
| SCHEMBL3960010 | 0.78 | HTR1D (0.40) | SIGMAR1HTR7DRD2DRD3HTR1A | |
| SCHEMBL3960016 | 0.78 | HTR1D (0.40) | SIGMAR1HTR7DRD2DRD3HTR1A | |
| SCHEMBL4763276 | 0.78 | HTR1A (0.44) | SIGMAR1HTR7DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL27740057 | 0.77 | HTR1D (0.39) | SIGMAR1DRD2DRD3HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL27740058 | 0.77 | HTR1D (0.39) | SIGMAR1DRD2DRD3HTR1ACYP1A2 | |
| SCHEMBL3957776 | 0.77 | HTR7 (0.49) | HTR7DRD2DRD3DRD4 | |
| SCHEMBL3957782 | 0.77 | HTR7 (0.49) | HTR7DRD2DRD3DRD4 | |
| SCHEMBL3958641 | 0.77 | HTR7 (0.49) | HTR7DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | disclosed |
| EP-1928860-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H.Lundbeck A/S (DK) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007019867-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | HTR2C, HTR2A, HTR5A | SIGMAR1 172/4885HTR7 20/4885DRD2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.