Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.57 |
| ▸ | CNR2 | P34972 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153161 | 0.94 | ALDH1A1 (0.52) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL10374502 | 0.83 | ALDH1A1 (0.51) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL23527433 | 0.81 | ALDH1A1 (0.46) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL23527421 | 0.78 | MAOA (0.55) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL6273719 | 0.76 | GABRA1 (0.49) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL10494619 | 0.75 | XDH (0.48) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL1245219 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL24650531 | 0.73 | XDH (0.47) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| SCHEMBL2732487 | 0.73 | MAOA (0.48) | GABRA1GABRB2CNR2ALDH1A1MAPT | |
| Magnolol SCHEMBL132477 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2CNR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094938-B1 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2006-08-22 | — | — | US | claimed |
| CN-101180249-B | Fluorene derivative, transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer | MITSU CHEMICALS INC | 2012-06-20 | — | — | CN | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20090076315-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED FLUORENES | FINA TECHNOLOGY, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-7473813-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| CN-101180249-A | Fluorene derivative, transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer | MITSUI CHEMICALS INC (JP) | 2008-05-14 | — | — | CN | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-7094938-B1 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2006-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | TFDP2, ZKSCAN2, MDM4 | GABRA1 3743/4885GABRB2 3889/4885CNR2 1898/4885 |
| US-20090076315-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED FLUORENES | TFDP2, ZKSCAN2, MDM4 | GABRA1 3743/4885GABRB2 3889/4885CNR2 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.