Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13881529 | 0.90 | RXFP1 (0.48) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL3969542 | 0.79 | CASP3 (0.40) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL13881531 | 0.79 | RXFP1 (0.60) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL3970605 | 0.79 | PRNP (0.79) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL4138770 | 0.78 | IDO1 (0.43) | ALDH1A1CASP3DHODHGCGRCYP1A2 | |
| SCHEMBL4146761 | 0.78 | KDM4E (0.48) | ALDH1A1 | |
| SCHEMBL3970468 | 0.78 | ALDH1A1 (0.79) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL13881528 | 0.78 | ALDH1A1 (0.60) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL27684995 | 0.78 | RXFP1 (0.65) | RXFP1PRNPPPARGNR2E3NCOR2 | |
| SCHEMBL3961796 | 0.77 | RXFP1 (0.48) | RXFP1PRNPPPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041904-A1 | QUINOLINE COMPOUNDS HAVING AN ACTIVITY AGAINST THE GABAB RECEPTOR | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009041904-A1 | QUINOLINE COMPOUNDS HAVING AN ACTIVITY AGAINST THE GABAB RECEPTOR | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | WO | disclosed |
| US-20090088441-A1 | Quinoline Compounds | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | US | disclosed |
| US-20090088441-A1 | Quinoline Compounds | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | US | disclosed |
| US-20090088441-A1 | Quinoline Compounds | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088441-A1 | Quinoline Compounds | GABRB1, HRH2, GABRA5 | RXFP1 40/4885PRNP 3104/4885PPARG 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.