SCHEMBL3962

SCHEMBL3962

FS(F)(F)(F)(F)c1cccc(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 1/20 0.42
KDM1A O60341 2/20 0.41
AKR1C3 P42330 2/20 0.38
AKR1C2 P52895 2/20 0.38
WDR5 P61964 1/20 0.36
C1S P09871 1/20 0.35
PARP1 P09874 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
IDO1 P14902 2/20 0.34
AGXT P21549 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12353999 0.81 ALDH1A1 (0.39) ALDH1A1MAPK1KDM1AC1SPARP1
SCHEMBL1966415 0.81 KDM1A (0.48) KDM1AAKR1C3AKR1C2PTGS1PTGS2
SCHEMBL816335 0.73 PDE2A (0.32) WDR5TDP1
SCHEMBL15108851 0.72 ACHE (0.44) MAPK1KDM1AAKR1C3AKR1C2PARP1
SCHEMBL4620762 0.71 CYP2A6 (0.50) ALDH1A1WDR5
SCHEMBL5000 0.71
SCHEMBL25037230 0.70 ALDH1A1 (0.42) ALDH1A1KDM1AAKR1C3AKR1C2PARP1
SCHEMBL1633970 0.70 CYP3A4 (0.52) ALDH1A1MAPK1KDM1AAKR1C3AKR1C2
SCHEMBL1635377 0.70 KDM1A (0.41) KDM1AAKR1C3AKR1C2PTGS1PTGS2
SCHEMBL816860 0.70 ACHE (0.52) ALDH1A1MAPK1KDM1AAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102224147-B Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2015-03-18 CN claimed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
EP-4665717-A2 USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS Insmed Incorporated (US) 2025-12-24 EP disclosed
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-20 US disclosed
EP-4570800-A1 CRYSTAL FORM OF PYRIDINOPYRIMIDINONE COMPOUND, ACID SALT THEREOF, CRYSTAL FORM OF ACID SALT THEREOF, AND USE Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) 2025-06-18 EP disclosed
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT ABBVIE INC (US) 2025-05-22 US disclosed
EP-4536639-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY Oregon Health & Science University (US) 2025-04-16 EP disclosed
CN-119487038-A KRAS G12D modulating compounds 吉利德科学公司 2025-02-18 CN disclosed
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2025-01-16 US disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 EP disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
CN-101475519-A Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines SANOFI AVENTIS DEUTSCHLAND (DE) 2009-07-08 CN disclosed
CN-100480237-C Process for preparing 4-pentafluorosulfanylbenzoylguanidines AVENTIS PHARMA GMBH (DE) 2009-04-22 CN disclosed
CN-100445265-C Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same AVENTIS PHARMA GMBH (DE) 2008-12-24 CN disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed
CN-1878753-A Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates AVENTIS PHARMA GMBH (DE) 2006-12-13 CN disclosed
CN-1878754-A Process for preparing 4-pentafluorosulfanylbenzoylguanidines AVENTIS PHARMA GMBH (DE) 2006-12-13 CN disclosed
CN-1878755-A Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same AVENTIS PHARMA GMBH (DE) 2006-12-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY EPX, TFEB, EPHX1 ALDH1A1 2498/4885MAPK1 4158/4885KDM1A 2980/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA ALDH1A1 2190/4885MAPK1 794/4885KDM1A 4556/4885
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 ALDH1A1 4238/4885MAPK1 2543/4885KDM1A 4149/4885
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT BCL2, BAX, BCL2L1 ALDH1A1 4457/4885MAPK1 3342/4885KDM1A 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.