Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23951296 | 0.79 | TRPV1 (0.39) | TRPV1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4472332 | 0.78 | CCR5 (0.43) | TRPV1KDM4EEPHX1ALDH1A1HTT | |
| SCHEMBL3965802 | 0.77 | TRPV1 (0.43) | TRPV1KDM4EEPHX1 | |
| SCHEMBL4028215 | 0.77 | MEN1 (0.46) | TRPV1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13870115 | 0.77 | PAK1 (0.49) | TRPV1KDM4EEPHX1ALDH1A1HPGD | |
| SCHEMBL4022010 | 0.76 | KMT2A (0.60) | TRPV1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL23951691 | 0.75 | ROCK2 (0.47) | KDM4E | |
| SCHEMBL23951520 | 0.75 | ROCK2 (0.47) | KDM4E | |
| SCHEMBL13865720 | 0.75 | PAK1 (0.50) | TRPV1KDM4ESMN1; SMN2TSHRPAK1 | |
| SCHEMBL2359677 | 0.74 | KDM4E (0.56) | TRPV1KDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528150-B2 | Urea derivatives having vanilloid receptor antagonist activity | GLAXO GROUP LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |
| US-20060178397-A1 | Urea derivatives having vanilloid receptor antagonist activity | GLAXO GROUP LIMITED (GB) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178397-A1 | Urea derivatives having vanilloid receptor antagonist activity | UTS2R, TRPV1, TACR1 | TRPV1 2/4885KDM4E 2776/4885EPHX1 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.