Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5168607 | 0.72 | CYP3A4 (0.35) | ALDH1A1SIGMAR1 | |
| SCHEMBL2912861 | 0.72 | CYP3A4 (0.35) | ALDH1A1SIGMAR1 | |
| SCHEMBL3185842 | 0.71 | TSHR (0.36) | HTR2CLMNANPC1RAB9ATSHR | |
| SCHEMBL4450995 | 0.70 | LMNA (0.33) | HTR2CLMNATSHRACHESLC6A2 | |
| SCHEMBL301552 | 0.69 | NPC1 (0.38) | LMNANPC1RAB9ATSHRACHE | |
| SCHEMBL4459830 | 0.69 | TSHR (0.35) | HTR2CTSHRACHESLC6A2SLC6A3 | |
| SCHEMBL3170606 | 0.69 | TSHR (0.35) | HTR2CLMNANPC1RAB9ATSHR | |
| SCHEMBL7596880 | 0.69 | NPC1 (0.38) | HTR2CLMNANPC1RAB9ATSHR | |
| SCHEMBL11056512 | 0.69 | TSHR (0.43) | LMNANPC1RAB9ATSHRACHE | |
| SCHEMBL11029955 | 0.68 | CYP3A4 (0.35) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414783-B1 | METHOD FOR THE PRODUCTION OF AMINES BY REDUCTIVE AMINATION OF CARBONYL COMPOUNDS UNDER TRANSFER-HYDROGENATION CONDITIONS | EVONIK DEGUSSA GMBH (DE) | 2009-07-15 | — | — | EP | disclosed |
| US-7230134-B2 | Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions | DEGUSSA AG (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20040267051-A1 | Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions | EVONIK DEGUSSA GMBH (DE) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267051-A1 | Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions | HNMT, AADAT, ADH5 | HTR2C 1957/4885LMNA 2090/4885NPC1 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.