SCHEMBL3964697

SCHEMBL3964697

CC1=Cc2c(cc(C(C)C)cc2C(C)C)C1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
FABP3 P05413 2/20 0.36
FABP4 P15090 2/20 0.36
FABP5 Q01469 1/20 0.35
ALDH1A1 P00352 1/20 0.32
ROCK2 O75116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453124 0.80
SCHEMBL4653379 0.75 METAP2 (0.41)
SCHEMBL6058578 0.74 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL7047520 0.73 GABRA1 (0.40) GABRA1GABRB2
SCHEMBL26497823 0.66
SCHEMBL3079552 0.65 GABRA1 (0.52) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL4837877 0.64 GABRA1 (0.38) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27362538 0.64 LMNA (0.39) ALDH1A1
SCHEMBL7949964 0.63 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL28407137 0.63 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262197-B1 AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION TARGOR GMBH (DE) 2001-07-17 US claimed
US-5670681-A Process for preparing a carbon-bridged biscyclopentadiene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US claimed
US-12398167-B2 Process for producing metallocenes LANXESS ORGANOMETALLICS GMBH (DE) 2025-08-26 US disclosed
EP-3917938-A1 PROCESS FOR PRODUCING METALLOCENES LANXESS Organometallics GmbH (DE) 2021-12-08 EP disclosed
CN-113366004-A Process for producing metallocenes 朗盛奥诺麦特里克斯有限责任公司 2021-09-07 CN disclosed
WO-2020156998-A1 PROCESS FOR PRODUCING METALLOCENES LANXESS ORGANOMETALLICS GMBH (DE) 2020-08-06 WO disclosed
EP-3686209-A1 PROCESS FOR PRODUCING METALLOCENES LANXESS Organometallics GmbH (DE) 2020-07-29 EP disclosed
EP-1622948-B1 PROCESS FOR POLYMERIZING 1-BUTENE BASELL POLYOLEFINE GMBH (DE) 2019-11-20 EP disclosed
CN-104271586-B Ansa-metallocene compounds and use the method that this compound prepares loaded catalyst LG CHEM, LTD. (KR) 2016-11-30 CN disclosed
US-7579423-B2 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2009-08-25 US disclosed
US-20080275254-A1 Process for polymerizing 1-butene BASELL POLYOLEFINE GMBH (DE) 2008-11-06 US disclosed
EP-0704454-A2 Process for the preparation of a bridged metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed
CN-1107854-A Metalocenes compound HOECHST AG (DE) 1995-09-06 CN disclosed
EP-0659757-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
US-5374752-A Catalyst system containing metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-20 US disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed
US-5328969-A Cocatalyst of an aluminoxane and metallocene HOECHST AKTIENGELLSCHAFT (DE) 1994-07-12 US disclosed
EP-0545303-A1 Process for preparing high molecular weight polyolefins HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed
EP-0545304-A1 Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275254-A1 Process for polymerizing 1-butene C9, CHRM1, C1S GABRA1 801/4885GABRB2 1679/4885FABP3 4866/4885
US-12398167-B2 Process for producing metallocenes CYP4F2, PRDX2, PRXL2A GABRA1 4474/4885GABRB2 4125/4885FABP3 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.